Investigation of High Molecular Weight Size Variant Formation in AntibodyDrug Conjugates: Microbial Transglutaminase-Mediated Crosslinking
Time: 2:30 pm
day: Day One
Details:
- Reviewing extended characterization of HMW size variants in mTG-mediated ADCs
- Identifying primary source of increased level of HMW size variants
- Exploring approaches to minimize HMW size variants formation in in mTG-mediated ADCs
