Ashley Mullan

Ashley Mullan

Company: AstraZeneca

Job title: Senior Scientist


Implementing Novel Methods & Strategies for Characterizing Fc Effector Functions of Antibody Drug Conjugates 10:00 am

ADCs with Fc effector functions pose challenges to CMC, including requirements for in-depth characterization and control which can be difficult to navigate in early development phases due to lack of in vivo and/or clinical data Traditional methods of assessing Fc effector functions, such as reporter gene bioassays, can be over-sensitive to small changes in early…Read more

day: Day Two

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